CBG: Side Effects and What You Should Know

17. 11. 2023

CBG, often referred to as the "mother" cannabinoid, is one of the many active compounds found in cannabis. Its medicinal potential, which includes its anti-inflammatory effects and ability to fight bacteria, makes it an appealing option for many people looking for alternative treatments. Like any substance, however, it carries with it potential side effects. Can CBG cause fatigue? Can it affect the effectiveness of other medications? And does CBG have more unwanted side effects than CBD? If you're considering incorporating CBG into your lifestyle, continue reading this article.

What is CBG?

CBG, full name cannabigerol, is one of more than a hundred cannabinoids found in the cannabis plant. Cannabinoids are chemical compounds that act on the endocannabinoid system in the human body and therefore can have a number of therapeutic effects.

CBG is often referred to as the 'parent' cannabinoid because many other cannabinoids are developed from it, including THC and CBD. Cannabigerol acid (CBGA) accumulates in young cannabis plants. As the plant matures, enzymes in the plant convert CBGA into one of the main cannabinoid acids - THCA, CBDA and CBCA. Once this conversion is complete, the remaining amount of CBGA can be decarboxylated into the CBG form.

The difference between CBG, CBD and THC:

CBG: CBG is considered the precursor to many other cannabinoids. It has weaker psychoactive effects and is known for its anti-inflammatory and antibacterial properties.
CBD: is a non-psychoactive cannabinoid that is known primarily for its therapeutic effects, especially against epilepsy, anxiety and pain.
THC: is the main psychoactive substance in cannabis, which gives users a feeling of euphoria.

Therapeutic effects of CBG

Although CBG is less well known than its counterparts CBD and THC, it has received increasing attention in recent years for its potential therapeutic effects. Below is a list of these:

Anti-inflammatory effects: CBG can be a potent anti-inflammatory that is useful for conditions such as Crohn's disease.
Antibacterial effects: some studies suggest that CBG may fight bacteria, especially those that are resistant to traditional antibiotics.
Neuroprotective effects: CBG can protect nerve cells from damage, which is important in neurodegenerative diseases such as Parkinson's disease.
Slowing the growth of cancer cells: there is evidence that CBG can inhibit the growth of certain types of cancer cells.
Treatment of glaucoma: CBG can reduce intraocular pressure, which is key to treating glaucoma.
Appetite stimulation: for people suffering from anorexia or other eating disorders, CBG can increase appetite.

Side effects of CBG

Although CBG is generally considered safe, there are several potential side effects that users should watch out for:

Fatigue: some users report feeling tired or sleepy after taking CBG, similar to CBD. To start, it is recommended to start with a low dose and see how the body reacts to it.
Drug interactions: CBG can affect the way your body processes certain medications, which can increase or decrease the effectiveness of those medications.
Changes in appetite and dry mouth: some users experience mild changes in appetite and dry mouth after taking CBG.
Decrease in blood pressure: CBG can slightly lower blood pressure, which can be a problem for those who already have low blood pressure or are taking blood pressure-lowering medications.
Digestive problems: some people may experience mild digestive problems such as diarrhea or nausea after taking CBG.
Increased sensitivity to light: some users report increased sensitivity to light after consuming CBG products.
Dizziness: CBG, like many other cannabinoids, can cause dizziness in some people, especially when combined with other drugs or substances.
Sweating: some people may experience increased sweating after taking larger doses of CBG.

How often do these side effects occur?

The frequency of these side effects depends on many factors, including dosage, individual sensitivity, and interactions with other substances or medications a person may be taking. Because research on CBG is still in its early stages, accurate data on the frequency of side effects are not always available.

While some side effects, such as fatigue, may be relatively common, especially at higher doses, others, such as digestive problems, may occur less frequently. However, it is important to take extra care and increase the dose of CBG gradually so that any side effects can be identified and addressed.

CBG vs. other cannabinoids

CBG:

Side effects: fatigue, drug interactions, changes in taste, dry mouth, decreased blood pressure, digestive upset, increased sensitivity to light, dizziness, and sweating.
Main benefits: anti-inflammatory, pain relieving, neuroprotective.

CBD:

Side effects: fatigue, dry mouth, decreased appetite, diarrhea, drug interactions, low blood pressure.
Main benefits: anti-inflammatory, pain-relieving, anti-anxiety, anti-spasmodic and neuroprotective.

THC:

Side effects: increased heart rate, dry mouth, red eyes, slower reactions, anxiety or paranoia, dizziness, impaired short-term memory, increased appetite.
Main benefits: pain relief, appetite support, counteracts nausea and vomiting, prevents muscle cramps.

How to take CBG?

Start with a lower dose: if you are starting with CBG, start with the lowest possible dose and gradually increase it until you find the optimal amount to suit your needs.
Product selection: choose a quality CBG product from a trusted manufacturer. Always read labels and check to see if the product contains a third-party certificate of analysis that guarantees that the CBG content matches what is stated on the label.

Cautions about combining CBG with other medications or dietary supplements:

Drug interactions: like many other substances, CBG can affect the way your body metabolizes other drugs. This can increase or decrease the effects of these medications. If you are concerned about possible interactions, you should contact your doctor.
Alcohol: it is recommended to avoid drinking alcohol while taking CBG, as this combination may increase the risk of unwanted side effects.
Dietary supplements: if you are taking dietary supplements, especially those that affect blood pressure, sleep or anxiety, talk to your doctor about possible interactions with CBG.

A few words in conclusion

Cannabigerol (CBG) is one of the many cannabinoids found in cannabis. Although it is less well known than THC and CBD, its therapeutic effects are gaining increasing attention. As with all dietary supplements and medicines, it is important to inform yourself about possible side effects and interactions with other substances. Although most people tolerate CBG well, it is still important to approach its use with caution, start with a low dose, and consult a doctor about possible drug interactions. Awareness and caution can ensure that you take full advantage of all the benefits CBG has to offer without experiencing unwanted side effects.

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