- Studies show that the healing effect of natural cannabis is more beneficial than its synthetic isolates
- The therapeutic effect of cannabinoids lies in their synergy - the so-called "entourage effect"
- Only 1.8% of patients prefer synthetic THC over natural ones, studies
If you take a careful look at the cannabis buds, you will notice that they are covered with a layer of sticky crystalline resin. This resin contains tintstherapeutically active substances known as hemp and terpenoids. We assume that you are already familiar with THC and CBD.
However, these two cannabinoids are only part of many other substances that contribute to the outcome of cannabis. Interactive synergy between cannabis ingredients is called "entourage effect". Once you understand the synergy function, youll find out why drugs containing only are isolated THCand.
Artificial "Marijuana" or Synthetic Cannabinoids
In the United States, there are drugs such as Marinol (dronabinol) or Cesamet (nabilone), which contain only synthetically isolated THC. There is a similar drug in the Czech Republic called Sativex, but it contains both synthetic THC and CBD in a 1: 1 ratio. Mostly Marinol or Cesamet is prescribed to treat nausea in cancer patients. However, their effectiveness is still doubtful.
A 2011 survey that explored various methods of consuming cannabis shows that only 1.8% of 953 patients prefer synthetic THC in the form of pills from inhalation of vapors or ingestion of cannabis extracts. In addition, the time before the desired effects of synthetic THC appear may take several hours, while inhalation of vapors acts immediately.
CBD treatment in the form of capsules, concentrates, or even under-tongue sprays has come to the forefront in recent years after the media cracking around Charlotte's Web. The Sharlotin Spider Web is a non-psychoactive variety, with a low THC content (<0.3%) and a high CBD content that has been used as a remedy for epilepsy for a Colorado girl, Sharlot Figi. This miraculous treatment pushed someone right awayAmerican States to legalize CBD.
Synthetic CBD and THC isolates or extracts from industrial cannabis are still a good choice for most patients, especially if they do not have access to complete medicine. Synthetic alternatives play an important role both in medicine and as a cornerstone for the introduction of complete cannabis legalization. However, treatment with the whole cannabis plant can offer us much more.
Complete herbal medicine
The term "whole plant medicine" is used to describe a treatment using the full spectrum of medicinal substances that occur in cannabis. In the picture above you can see the most common cannabinoids as well as a description of their properties and effects. If you want to see a higher resolution image, please visit Instagram profile .
As you can see, cannabis contains many other substances that are able to synergistically achieve much better therapeutic effects than only isolated THC or CBD. and awareness of the diversity of other cannabinoids and terpenes contained in cannabis. Hopefully, vbwe will also see varieties that will, in addition to balancing the ratio between CBD and THC ( CBD Varieties ) , also focus on other cannabinoids and terpenes.
Synergy between cannabinoids and terpenes
The variety of chemicals in a cannabis plant is intriguing in itself, but research that deals with cannabinoid and terpene cooperation reveals a whole new level of complexity.
Neurolog MUDr. Ethan Russo is a long-time science expert in cannabinoid function in the human body. In his study "Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effect" , he describes in detail how substances in hemp interact with each other and change their original mechanisms.
Even a slight difference in the terpene profile of a plant can have a noticeable effect on the final effect. For example:
- Terpen myrcene increases the permeability of the blood-brain barrier through which a greater number of active substances can pass.
- Terpen pinene in turn reduces THC negative effects on cognitive function and memory.
- The combination of myrcene, pinene, and caryophyllene helps alleviate anxiety.
- The co-administration of limonel and linalool terpene and CBG cannabinoid results promisinglyy for the treatment of MRSA (Methicillin-Resistant Golden Staphylococcus)
- The combination of the same terpenes and cannabinoid CBD has the potential to treat acne.
- THC together with CBN induces a powerful sedative effect.
But these examples are just the tip of the iceberg. The whole cannabis plant offers much more. If we can understand the true function of terpenes and their synergies, a whole new world of medicine will open up to us. The idea of how many human lives can change to better solve this complex medical mystery is truly amazing.