Theoretical explanation for decreased BMI and the risk of obesity in cannabis users (STUDY)

  • Theoretical explanation for decreased BMI and the risk of obesity in cannabis users (STUDY)

What is the relationship between cannabis and body mass index?

Extract from the study

Introduction:

Obesity is a very resistant disease to treatment and is associated with a large number of health complications, which can be very serious. Since the 1960s, adult obesity has tripled in America.

Recent studies show that increasing the intake of omega-6 and omega-3 fatty acids increases the risk of obesity. This process is due to increased endocannabinoid AEA and 2-AG signals, which cause excessive stimulation of CB1R and lead to increased caloric intake, decreased metabolic rate and weight gain.

Cannabis, or THC, also stimulates CB1R and increases calorie intake during acute exposure.

Study objectives:

Determine the relationship between cannabis and body mass index (BMI) and offer a theoretical explanation of their relationship.

Results:

Current meta-analysis reveals a significant decrease in body mass index and obesity rates in cannabis users in conjunction with high calorie intake.

Theoretical explanation:

For the first time, we can provide a causative explanation of this paradox. Rapid and long-lasting down-regulation of CB1R followed by the urgent use of cannabis reduces energy levels and increases metabolic rate.

Keywords: cannabis, body mass index, BMI, obesity, omega-6 fatty acids, theory


Authors: Thomas M. Clark, Jessica M. Jones, Alexis G Hall, Sara A. Tabner, Rebecca L. Kmiec
You can read more of this study at: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340377/. The whole study is in English.

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