How to increase the effect of CBD?

6 min read

How to increase the effect of CBD?

Cannapio seedsOur own brandBrowse ›Tip for this articleAuto Banana OG Kush - autoflowering seeds 5 pcs Cannapio€19.30Browse ›Tip for this articleAuto Pure Haze - 3pcs Cannapio Autoflowering Seeds€9.20Browse ›
Today, we will look at the opinion of 5 experts in the field of cannabis science on the potential of CBD itself versus CBD applied with other cannabinoids

In the fascinating world of collectible cannabis genetics, CBD has emerged as an extraordinary cannabinoid that sparks the interest of collectors and enthusiasts alike. This non-psychoactive compound, present in both industrial and medicinal varieties, has revolutionized our understanding of the aromatic and chemical profile of cannabis.

Collectible seeds with CBD-rich profiles have gained popularity due to the unique properties this cannabinoid brings to the plant's genetics. Its ability to interact with the endocannabinoid system without producing psychoactive effects makes it a particularly valued element in the collection of genetic material.

However, a fundamental question arises among cannabis genetics experts: is CBD more valuable as an isolated compound, or does it reach its full potential when it is part of the full spectrum of cannabinoids naturally present in the plant?

CBD in the Context of Collectible Genetics

Collectible cannabis varieties rich in CBD feature unique characteristics that distinguish them in the seed market. These genetics have been developed to express specific cannabinoid profiles, where CBD can represent from a minority percentage to becoming the dominant cannabinoid.

The CBD phenomenon has transformed the landscape of seed collecting, especially in markets where legislation favors varieties with low THC content. Many breeders have specialized in developing genetic lines that maximize CBD expression, creating unique and complex aromatic profiles.

However, numerous cannabis genetics specialists maintain a critical stance regarding the exclusive focus on CBD. According to these experts, the true value of a genetics lies in the complete synergy of compounds that includes not only CBD and THC, but also the wide range of terpenes and flavonoids that characterize each specific variety.

This entourage effect represents the synergistic interaction between all active compounds present in the original genetics of the plant, suggesting that the most interesting properties emerge when these elements work together rather than in isolation.

Expert Perspectives on the Potential of CBD

To better understand this complex discussion, we have gathered the opinions of five recognized cannabis science specialists who work with genetics and cannabinoid profiles:

  • Jessica Peters, founder of Moxie Meds
  • Constance Finley, founder and director of Constance Therapeutics
  • Mary Lynn Mathre, RN, MSM, president of Patients out of Time
  • Eloise Theisen, RN, MSN, director at American Cannabis Nurses Association
  • Perry Solomon, MD, lead physician at HelloMD

Properties of CBD as an Isolated Compound

Mary Lynn Mathre highlights the multiple properties that characterize CBD-rich genetics: "Varieties with high CBD content are known for their anxiolytic, anti-inflammatory, anticonvulsant, neuroprotective, and bone growth-promoting profiles, among other distinctive characteristics."

Jessica Peters expands on this perspective: "CBD genetics express anti-inflammatory, anticonvulsant, neuroprotective, and antipsychotic properties. However, some of these characteristics may not fully manifest until the profile also includes some presence of THC. A particularly interesting aspect is the potential of CBD to influence neural circuits related to addiction."

Constance Finley offers a research-based view: "Multiple studies have documented the positive properties of CBD in relation to inflammation, pain, anxiety, psychosis, and seizures. However, it is important to note that most of these studies used genetics that contained some level of THC, whose phytotherapeutic properties had already been previously established."

Synergy between Cannabinoids and Other Compounds

Perry Solomon explains the mechanism of action: "CBD-rich genetics are recognized for inducing feelings of calm and relaxation. CBD interacts with CB2 receptors and delta-opioid receptors, manifesting calming, relaxing, antioxidant, sedative, and antidepressant properties without the psychoactive effects of THC. It also shows potential to influence gene expression related to amyloid plaque formation."

Jessica Peters emphasizes the importance of the complete composition: "The influence is tremendously significant. The fact that CBD is a plant-derived compound is fundamental to many of its properties. The THC:CBD ratio is the main variable - different ratios produce completely distinct effect profiles. For example, a 1:1 ratio is considered optimal for pain relief. Additionally, many terpenes show direct connections with cannabinoids, a phenomenon that is increasingly documented."

Eloise Theisen summarizes the matter concisely: "It seems that THC and CBD work best together, mutually balancing their potential side effects."

The Future of Cannabinoid Genetics

The evidence suggests that the most valuable genetics for collectors are those that maintain the full spectrum of compounds, including cannabinoids, terpenes, and flavonoids working in synergy. This "whole plant medicine" represents the most sophisticated approach to understanding and appreciating the true characteristics of each variety.

For CBD seed collectors, this means that the most interesting genetics are those that preserve the original chemical complexity of the plant, rather than those modified to express only isolated CBD.

The complete aromatic profile, resulting from the interaction between all these compounds, constitutes the true signature of each collectible genetics, making each variety a unique piece within a specialized collection.