Doctor Advises: What Is the Healthy Dosage of Cannabis

04/30/2018 8 min read

Healthy Cannabis Dosage? (Doctor's Advice)

You have certainly wondered many times about what amount of cannabis is actually optimal. In this article, Dr. Dustin Sulak will give you several tips that will help answer this question.

Understanding Cannabinoid Profiles: Expert Recommendations

Collector cannabis seeds represent invaluable genetic material with unique aromatic profiles and cannabinoid characteristics. Dr. Dustin Sulak, a leading researcher in the field, shares his observations on the optimal properties of various genetics, based on eight years of research.

"The key to understanding cannabinoid genetics lies in knowing their biochemical profiles", explains Dr. Sulak. According to his research, different strains show extremely diverse concentrations of active compounds - from minimal amounts to exceptionally high levels of cannabinoids.

Multiphase Response of Active Compounds

Cannabis genetics demonstrate atypical behavior compared to other plant materials. Unlike traditional herbs, where higher concentration always means stronger properties, cannabinoid genetics follow a more complex pattern.

When studying different collector strains, it has been established that gradually increasing the concentration of active compounds leads to enhanced effects up to a certain point. Beyond this threshold, however, properties may diminish while undesirable characteristics increase.

Users of collector materials who continue working with higher concentrations may observe the return of some therapeutic properties or even the appearance of new characteristics that do not manifest at lower levels. However, higher concentrations are significantly more expensive and usually bring more unwanted effects. Most researchers achieve better results at more moderate levels.

For them, less is more! One study focusing on 263 cancer patients divided them into several groups. The group receiving 21 mg daily of a THC and CBD combination reported significantly greater pain relief than the second group, which received 52 mg daily. In the third group, which consumed 83 mg daily, no significant pain relief was observed, but patients reported many more side effects.

"Cannabis genetics have the ability to induce different effects in different people depending on the strain and the amount."

How is this possible? The endocannabinoid system is a sensitive, physiological system designed to maintain balance at the cellular level. However, when cannabinoid receptors are overstimulated by high doses, cells draw their receptors inward, where they are subsequently recycled or degraded. The fewer cannabinoid receptors there are, the weaker the effects of cannabis. This applies especially when the dose is increased too much. This phenomenon is called "tolerance building" and is experienced by many people who consume cannabis regularly.

The "Therapeutic Window" of Collector Genetics

The term "therapeutic window" describes the range between the lowest effective amount and the amount that creates undesirable or unacceptable side effects. People with little or no experience with cannabis use typically have a very narrow "therapeutic window," while regular users develop a wider "window." This is due to the fact that individuals build tolerance to different effects of cannabis at different rates. They build tolerance to unwanted effects much faster than to desired ones.

Bidirectional Properties of Cannabinoid Profiles

Cannabis genetics have the ability to induce different effects in different people depending on the strain and concentration, which are sometimes called bidirectional. For example, people suffering from anxiety who consume a certain amount of cannabis may feel calmed. Other people who do not suffer from anxiety, however, may begin to experience anxiety when consuming the same amount. The same amount of two different cannabis strains can also produce opposite effects. One may cause stimulation, the other - drowsiness.

"By combining THC and CBD, you can make the most of all the benefits of cannabis and reduce the amount of unwanted effects."

Interestingly, the symptoms of cannabis overdose closely resemble those symptoms that cannabis is supposed to relieve when properly dosed: nausea, vomiting, diarrhea, sweating, cramps, trembling, anxiety, panic attacks, paranoia, impaired coordination and sleep. Extreme overdose can lead to hallucinations and even acute psychosis.

Fortunately, these symptoms soon subside and people usually return to their natural state within 12 to 24 hours. Although a person experiencing an overdose may feel as if they are dying, such an experience carries no toxicity or permanent damage. The only exceptions are people with unstable cardiovascular or psychiatric conditions and situations where the condition led to an accident.

Combination of THC and CBD in Collector Seeds

Although THC and CBD work through different mechanisms, they have many overlapping healing properties that include relieving pain, anxiety, seizures, and nausea. By combining THC and CBD, you can make the most of all the benefits of cannabis and reduce the amount of unwanted effects, such as the psychoactive effects of THC. This is excellent news for those cannabis users who want to use all the healing benefits of cannabis while keeping a clear head.

Exceptionally low doses of cannabis can be very effective, sometimes even more so than exceptionally high ones.

By combining CBD and THC, the aforementioned "therapeutic window" becomes even wider. However, users should be aware that this also increases the total amount of cannabinoids needed to treat symptoms and diseases.

As an example, we can cite the study of 177 cancer patients suffering from pain. One group received an oral spray containing THC, while the second group received an oral spray containing a combination of THC and CBD in an approximate 1:1 ratio. Both groups were allowed to gradually increase their dose until they experienced satisfactory relief. The THC group ended up with an average consumed amount of 27 mg daily. The THC+CBD group consumed on average nearly 60 mg daily but reported much greater pain relief. And I have noticed this in other patients as well. With the combination of THC and CBD, you can achieve better results, but you need to be prepared to consume a higher amount.

Extremely Low Concentrations in Genetic Material

Some researchers do well when working with extremely high amounts of cannabis (hundreds or thousands of milligrams daily). Everyone should work up to these extreme doses gradually, but some specialists achieve excellent results with microdosing - using minimal amounts of active compounds.

Collector seeds from Cannapio offer a rich variety of genetic profiles, allowing enthusiasts to study different cannabinoid compositions and terpene profiles. Each strain carries unique genetic information that determines its aromatic and biochemical characteristics.